10th July — 14:30 UTC (check local time) 

Rubén Deogracias
Ramón y Cajal Researcher and PI at the Institutes of Castilla y León, University of Salamanca. Speaking from Salamanca, Spain..

MSK1 regulates striatal development and psychiatric behaviours

MSK1 integrates BDNF-MeCP2 signaling to shape striatal GABAergic circuits during postnatal development. Using a novel Msk1IV KO mouse model, we show that MSK1 deficiency reduces striatal volume, impairs MSN morphology, disregulating GABAergic gene expression, causing psychiatric-like behaviours.